Complete List of Published Work in MyBibliography:

Peer reviewed publications in print or other media

(a) Original Research Publications

1. Willows JW, M Robinson, Z Alshahal, SK Morrison, G Mishra, H Cyr, M Blaszkiewicz, S DiPietro, E Paradie, L Liaw, PC Reifsnyder, D Harrison, KL Townsend*. Age-related changes to adipose tissue and peripheral neuropathy differ by mouse sex and genetic background, and are not mitigated by rapamycin longevity treatment. (Accepted and in press Aging Cell, 2023). *Corresponding Author
2. Blaszkiewicz M, G Gunsch, J Willows, M Gardner, A Sas, KL Townsend*. Adipose tissue myeloid-lineage neuroimmune cells express genes important for neural plasticity and regulate adipose innervation. (2022) Frontiers in Endocrinology 13:864925
3. Townsend KL*, E Pritchard, JM Coburn, YM Kwon, M Blaszkiewicz, MD Lynes, DL Kaplan, YH Tseng*. Silk hydrogel-mediated delivery of bone morphogenetic protein 7 directly to subcutaneous white adipose tissue increases browning and energy expenditure. (2022) Front Bioeng Biotechnol. 10:884601. * co-corresponding authors
4. Willows JW, M Blaszkiewicz and KL Townsend*. STAR Protocols: A clearing-free protocol for imaging intact whole adipose tissue innervation in mice. Cell Press, STAR Protocols. (2022, Vol 3(1), 101109) *Corresponding Author
5. Jensen G, KL Townsend*. Lineage tracing of adult stem cells in the mouse brain. (2022) JOVE, April 2022. *Corresponding Author
6. Willows JW, G Gunsch, E Paradie, M Blaszkiewicz, KL Townsend*. The presence of myelinated nerves and Schwann cells in adipose tissues, and changing Schwann cell phenotypes across metabolic states. (2023) Accepted and in press, iScience (also on BioRxiv Sept 8, 2022) *Corresponding Author
7. Paradie E, J Willows, M Blaszkiewicz, KL Townsend*. Adipose Tissue Schwann Cells: Identification and Diversity.  In Preparation, submission Summer 2021 to Glia.
8. G Jensen^, Beaulieu, A^, Carolyn Curtis, Magdalena Blaszkiewicz, Joshua Passarelli, Lydia Caron, Seth Thomas, Trevor Morin, Chris Aniapam, Ciara Brennan, Cameron Ford, Olivia Stevenson, Matthew Lynes, Diana Carlone, David Breault, Kristy Townsend*. Telomerase reverse transcriptase (TERT) as a novel and unique marker for quiescent stem cells in the adult mouse brain. (2021) Under Revised Resubmission; ^equal contributing first authors; *Corresponding Author
9. Johnson CP, D Taplin ML Gardner, MA Freitas, Kristy L. Townsend*. Cold-induced adaptations to the proteome of mouse subcutaneous white adipose tissue (scWAT) reveals proteins relevant for tissue remodeling and plasticity. (2022). Under Revised Resubmission. *Corresponding Author
10. Lynes MD, DL Carlone, KL Townsend, DT Breault, Y-H Tseng. Telomerase reverse transcriptase expression marks a population of rare adipose tissue stem cells. Stem Cells (2022), 40(1), 102- 111.
11. Blaszkiewicz M, KL Townsend*. Energy Balance and Neuroimmune Cells In Adipose Tissue (submission Oct 2021 to Frontiers special issue research topic: Crosstalk Between Adipose Tissue and Immune Cells.
12. Harling M, J Juybari, CP Johnson, KL Townsend, A Khalil, K Tilbury. Wavelet-based characterization of the spatial relationship of nerve and collagen in neuropathic adipose tissue. SPIE digital library, Feb 20, 2020, Proceedings Volume 11245, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXVII; 112450R (2020)
13. Blaszkiewicz M., Wood E., Koizar S., Willows J., Anderson R., Tseng Y-H., Godwin J., Townsend K.L.* The Involvement of Neuroimmune Cells in Adipose Innervation (Accepted and In Press at Molecular Medicine 26, Article number: 126 (2020)) *Corresponding Author
14. Willows J.W., Blaszkiewicz M., Lamore A., Borer S., Dubois A., Garner E., Breeding P., Tilbury K., Khalil A., Townsend K.L.* Visualization and analysis of whole depot adipose tissue innervation. (2021) BIORXIV/2019/788885 (Under revised re-submission to Cell Reports) *Corresponding Author
15. Townsend KL#, Colburn J, Pritchard E, Lynes MD, Blaszkiewicz M, Kwon YM, Kaplan DL, Tseng YH#. Silk-mediated delivery of BMP7 to white adipose tissue promotes browning and increases energy expenditure. Under Submission # Co-corresponding authors.
16. Blaszkiewicz M, Willows JW, Dubois AL, Waible S, DiBello K, Lyons LL, Johnson C., Paradie E., Banks N., Motyl K., Merilla M., Harrison B., Townsend K.L.* (2019) Neuropathy and neural plasticity in the subcutaneous white adipose depot. PLoS .ONE 14(9): e0221766. *Corresponding Author
17. Breeding PW, M Blaszkiewicz, K Townsend, A Khalil, KB Tilbury. Exploratory Investigations of the spatial relationships of collagen and nerves in subcutaneous white adipose tissue (scWAT) using 2-photon microscopy. SPIE Digital Library, Proceedings Volume 10882, Multiphoton Microscopy in the Biomedical Sciences XIX; 1088218 (2019)
18. Miller J#, M Blaszkiewicz#, C. Beaton, CP Johnson, S Waible, A Dubois, A Klemmer, M Kiebish, KL Townsend*. A peroxidized omega-3-enriched polyunsaturated diet leads to adipose and metabolic dysfunction. (2019) J Nutr Biochem. (64): 50-60. *Corresponding Author; # Equal contributing first authors
19. Townsend KL*, Madden C, Blaszkiewicz M, McDougall LM, Tupone D, Lynes DM, Yu P, Morrison S,Tseng YH*. Re-Establishment of energy balance in a male mouse model with POMC neuron deletion of BMPR1A. (2017) Endocrinology 158(12): 4233-4245. *Co-Corresponding Author.dies Conducted Through 2013. Under re-submission. *Corresponding Author. 
20. Asalone K. and KL Townsend*. The importance of social sciences in biomedical education and doctor-patient interactions.  (2017) Accepted with revisions at Journal of Young Investigators. *Corresponding Author
21. AL Waldron, Schroder PA, KL Bourgon, JK Bolduc, JL Miller, AD Pellegrini, AL Dubois, M Blaszkiewicz, KL Townsend, S Rieger. Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity. (2017) J Diabetes Complications, 32(3):249-257.
22. An D, Townsend KL, Lee MY, Getchell KM, Tseng YH, Hirshman MF, and Goodyear LJ. Akt2 Deficient Mice Have Altered Energy Metabolism and Mitochondrial Function in Brown Adipose Tissue. Under re-submission.
23. Williams J, Rosner BA, Townsend KL*, Effects of Intermittent Fasting on Body Weight and Dyslipidemia: A Meta-Analysis of Studies Conducted Through 2013. Under re-submission. *Corresponding Author.
24. Zhang H, Guan M, Huang TL., Townsend KL, An D, Schulz T, Winnay J, Mori M, Goodyear LJ, Tsang J, Tseng YH. MicroRNA Determines Brown Fat Differentiation and Thermogenic Function. (2015)  EMBO reports. 16(10):1378-9.
25. Xue R, Lynes MD, Dreyfuss J, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng Y-H. Clonal Analysis and Gene Profiling Identify Genetic Biomarkers of the Thermogenic Potential of Human Brown and White Preadipocytes. (2015) Nature Medicine 21(7), 760-8. PMID: 26076036
26. Stanford KI, Middelbeek RJW, Townsend KL, Lee M-Y, Takahashi H, So Kawai, Hitchcox KM, Markan KR, Hellbach K, Hirshman MF, Tseng Y-H, Goodyear LJ. A Novel Role for Subcutaneous Adipose Tissue in Exercise-Induced Improvements in Glucose Homeostasis. Diabetes. 64(6), 2014.  PMID
27. Schulz TJ, Huang P, Huang TL, McDougall LE, Townsend KL, Cypess AM, Mishina Y, Gussini E, Y.-H.Tseng. Impaired Development of Constitutive Brown Adipocytes Due to Loss of BMP Signaling Induces Compensatory Browning of White Adipose Tissue.  (2013) Nature Mar 21; 495(7441): 379-83.  PMID: 23485971 
28. Stanford KI, Middelbeek RJW, Townsend KL, An D, Hitchcox KM, Markan KR, Nakano K, Nygaard EB, Jung DY, Lee Y, Kim JK, Hirshman MF, Tseng YH, and Goodyear LJ. Brown Adipose Tissue Regulates Glucose Homeostasis and Insulin Sensitivity. (2013) J Clin Invest. Jan 2; 123(1):215-23. PMID: 23221344 
29. Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng Y-H, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Bluher M, Hsu SIH, Kulkarni RN. Ablation of TRIP-Br2, a novel regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. (2013) Nat Med. Feb;19(2):217-26.  PMID: 23291629 
30. Townsend KL, An D, Lynes MD, Huang TL, Goodyear LJ, and Tseng YH. Increased Mitochondrial Activity in BMP7-treated Brown Adipocytes, Due to Increased CPT1- and CD36-mediated Fatty Acid Uptake.  (2012) Antioxidants & Redox Signaling. 19(3), 243-57. PMID: 22938691
31. Townsend KL*, Suzuki R*, Huang TL, Jing E, Schulz T, Lee K, Taniguchi CM, Espinoza DO, McDougall LE, He TC, Kokkotou E, and Tseng YH. Bone Morphogenetic Protein 7 (BMP7) Reverses Obesity and Regulates Appetite Through a Central mTOR Pathway. (2012). FASEB J, 26(5): 2187-96. (* co-first authors) PMCID: PMC3336788
32. Schulz TJ, Huang TL, Tran TT, Zhang H, Townsend KL, Shadrach JL, Cerletti M, McDougall L, Giorgadze N, Tchkonia T, Schrier D, Falb D, Kirkland JL, Wagers AJ, and Tseng YH. Identification of Inducible Brown Adipocyte Progenitors Residing in Skeletal Muscle and White Fat. (2011). Proc Natl Acad Sci U.S.A., 108(1): 143-8. PMCID: PMC3017184

33. Townsend KL, Kunz TH, and Widmaier EP. Changes in body mass, serum leptin, and mRNA levels of leptin receptor isoforms during the premigratory period in Myotis lucifugus. (2008) J Comp Physiol [B]. 178(2): 217-23. PMID: 17962952

34. Townsend KL, Lorenzi MM, and Widmaier EP. High-fat diet-induced changes in body mass and hypothalamic gene expression in wild-type and leptin-deficient mice. (2008) Endocrine, 33(2):176-88. PMID: 18483882

35. Schulz LC, Townsend KL, Kunz TH, and Widmaier EP. Inhibition of Myotis lucifugus trophoblast invasiveness in vitro by immunoneutralization of leptin. (2007) General and Comp Endo, 150(1): 59-65. PMID: 16938297

36. Zhao J, Townsend KL, Schulz LC, Kunz TH, Li C, and Widmaier EP. Leptin receptor expression increases in placenta, but not hypothalamus, during gestation in Mus musculus and Myotis lucifigus. (2004) Placenta, 25: (8-9). PMID: 15450389

(b)  Reviews

1.     Johnson CP, M Blaszkiewicz, AL Dubois, J Willows, S Rieger, KL Townsend*. MMP-13 inhibition reverses diabetic neuropathy in skin and underlying adipose. In Preparation. *Corresponding Author

2.     Jensen GS, A Beaulieu, CD Curtis, M Blaszkiewicz, CW Greco, CJ Brennan, MD Lynes, D Breault, KL Townsend*. Mouse telomerase reverse transcriptase (mTERT) reveals a new niche of quiescent adult neural stem cells in the murine choroid plexus. In Preparation. *Corresponding Author

3.     Luiz Leiria*, Magdalena Blaszkiewicz*, Wenjie Chen, Sarah Lessard, TianLian Huang, Ruidan Xue, Laurie Goodyear, Herb Lin, Jodie Babitt, Kristy Townsend#, Yu-Hua Tseng#. Novel role for Hemojuvelin in the regulation of brown adipogenesis. *Equal first-author contribution; In Preparation. # Co-corresponding authors.

(c) Reviews, Chapters, Commentaries, Lay press, Other Media

  1. Jensen GS, NE Leon-Palmer, KL Townsend*. Bone Morphogenetic Proteins (BMPs) in the Central Regulation of Energy Balance and Adult Neural Plasticity. Invited Review, Metabolism (2021), 123:154837. PMID: 34331962. *Corresponding Author
  2. Mishra G, KL Townsend*. Sensory innervation and sensory neuropeptide functions in adipose tissues. Invited Review, Cell Metabolism, Submission Winter 2021.
  3. E Paradie, KL Townsend*. Glial cell types of the peripheral nervous system, implications for metabolically important tissues. Invited Review, Trends in Endocrinology and Metabolism, Submission Winter 2021.
  4. Hussein A, C Ford, KL Townsend*. Plasticity of the Adult Hypothalamus: cell types and mechanisms in the central regulation of energy balance. (Accepted presubmission inquiry to Endocrinology, submission Winter 2021).
  5. Passarelli J, S Nimjee, KL Townsend*. Adult neural plasticity in the setting of stroke. (review article under revised resubmission, 2022)
  6. Townsend KL. The re-emergence of adipose innervation as a research focus. Invited Commentary article for Nature Reviews Endocrinology 16, 127-128 (2020)
  7. Blaszkiewicz M, C Johnson, J Willows, KL Townsend*. The Importance of Peripheral Nerves in Adipose Tissue for the Regulation of Energy Balance. (2019) (invited review article for “New Players in Adipocyte Biology” special issue of Biology 2019, 8(1), 10; *Corresponding Author
  8. Townsend KL (2016). The science of appetite. Zest, Summer 2016 issue.
  9. Blaszkiewicz M, KL Townsend*. (2016) Adipose Tissue and Energy Expenditure: Central and Peripheral Neural Activation Pathways. Current Obesity Reports Jun;5(2):241-50. *Corresponding Author
  10. Townsend KL (2015). Brain eating: The science behind taste, hunger, and why we either love or hate certain foods. Zest, Summer 2015 issue.
  11. Townsend KL and YH Tseng. (2015). Of Mice and Men: Novel Insights Regarding Constitutive and Recuitable Brown Adipocytes. Invited Review for International Journal of Obesity Supplements 5. S15-20.
  12. Townsend KL and YH Tseng. (2014). Brown Fat Fuel Utilization and Thermogenesis. Invited Review for Trends in Endocrinology and Metabolism 25(4):168-177. *chosen by editorial board as Top 10 Best Articles of 2014 in TEM. * ranked as Science Direct top 25 most downloaded articles for Oct-Dec 2014.
  13. Townsend KL and YH Tseng. (2012). Brown Adipose Tissue: Recent Insights into Development, Metabolic Function, and Therapeutic Potential. Invited Review for inaugural issue of the new journal Adipocyte, 2012 Jan 1(1) 13-24.


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